rat SAE1 shRNA silencing AAV

Cat. No: shAAV-291989

Availability: 6-8 weeks

Name: AAV-r-SAE1-shRNA

This is an AAV expressing shRNA for silencing of Rat Sae1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Sae1
Gene Name: SUMO1 activating enzyme subunit 1
Gene ID: 308384
Gene Synonyms: Uble1a
ORF Size: 1050 bp
RefSeq#: NM_001012063
Gene Description: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.