rat TINF2 shRNA silencing AAV

Cat. No: shAAV-291875

Availability: 4-5 weeks

Name: AAV-r-TINF2-shRNA

This is an AAV expressing shRNA for silencing of Rat Tinf2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Tinf2
Gene Name: TERF1 interacting nuclear factor 2
Gene ID: 290232
ORF Size: 1194 bp
RefSeq#: NM_001006962
Gene Description: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.