rat YME1L1 shRNA silencing AAV

Cat. No: shAAV-291522

Availability: 4-5 weeks

Name: AAV-r-YME1L1-shRNA

This is an AAV expressing shRNA for silencing of Rat Yme1l1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Yme1l1
Gene Name: YME1-like 1 ATPase
Gene ID: 114217
Gene Synonyms: FtsH1
ORF Size: 2148 bp
RefSeq#: NM_053682
Gene Description: Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.