rat KCNMB2 shRNA silencing AAV

Cat. No: shAAV-291482

Availability: 6-8 weeks

Name: AAV-r-KCNMB2-shRNA

This is an AAV expressing shRNA for silencing of Rat Kcnmb2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Kcnmb2
Gene Name: potassium calcium-activated channel subfamily M regulatory beta subunit 2
Gene ID: 294961
Gene Synonyms: Kcmb2
ORF Size: 525 bp
RefSeq#: NM_176861
Gene Description: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.