rat TGFB1 shRNA silencing AAV

Cat. No: shAAV-291401

Availability: 4-5 weeks

Name: AAV-r-TGFB1-shRNA

This is an AAV expressing shRNA for silencing of Rat Tgfb1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Tgfb1
Gene Name: transforming growth factor, beta 1
Gene ID: 59086
Gene Synonyms: Tgfb
ORF Size: 1173 bp
RefSeq#: NM_021578
Gene Description: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.