rat PHB2 shRNA silencing AAV

Cat. No: shAAV-291350

Availability: 4-5 weeks

Name: AAV-r-PHB2-shRNA

This is an AAV expressing shRNA for silencing of Rat Phb2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Phb2
Gene Name: prohibitin 2
Gene ID: 114766
Gene Synonyms: Bap; Bap-37; Bap37; Bcap27; Bcap37
ORF Size: 900 bp
RefSeq#: NM_001013035
Gene Description: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.