rat IRGM shRNA silencing AAV

Cat. No: shAAV-291251

Availability: 4-5 weeks

Name: AAV-r-IRGM-shRNA

This is an AAV expressing shRNA for silencing of Rat Irgm.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Irgm
Gene Name: immunity-related GTPase M
Gene ID: 303090
Gene Synonyms: Ifggd3; Ifi1
ORF Size: 1236 bp
RefSeq#: NM_001012007
Gene Description: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).