rat GPR177 shRNA silencing AAV

Cat. No: shAAV-290514

Availability: 6-8 weeks

Name: AAV-r-GPR177-shRNA

This is an AAV expressing shRNA for silencing of Rat Wls.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Wls
Gene Name: wntless Wnt ligand secretion mediator
Gene ID: 362065
Gene Synonyms: Gpr177
ORF Size: 1626 bp
RefSeq#: NM_199408
Gene Description: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).