rat HMGB1 shRNA silencing AAV

Cat. No: shAAV-290383

Availability: 4-5 weeks

Name: AAV-r-HMGB1-shRNA

This is an AAV expressing shRNA for silencing of Rat Hmgb1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Hmgb1
Gene Name: high mobility group box 1
Gene ID: 25459
Gene Synonyms: Ac2-008; Hmg1
ORF Size: 648 bp
RefSeq#: NM_012963
Gene Description: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).