rat CBARA1 shRNA silencing AAV

Cat. No: shAAV-290305

Availability: 6-8 weeks

Name: AAV-r-CBARA1-shRNA

This is an AAV expressing shRNA for silencing of Rat Micu1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Micu1
Gene Name: mitochondrial calcium uptake 1
Gene ID: 365567
Gene Synonyms: Cbara1
ORF Size: 1434 bp
RefSeq#: NM_199412
Gene Description: Key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. May act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.