rat UNC119 shRNA silencing AAV

Cat. No: shAAV-290281

Availability: 4-5 weeks

Name: AAV-r-UNC119-shRNA

This is an AAV expressing shRNA for silencing of Rat Unc119.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Unc119
Gene Name: unc-119 lipid binding chaperone
Gene ID: 29402
Gene Synonyms: RRG4; Uncl19
ORF Size: 723 bp
RefSeq#: NM_017188
Gene Description: Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.