rat BAD shRNA silencing AAV

Cat. No: shAAV-290176

Availability: 4-5 weeks

Name: AAV-r-BAD-shRNA

This is an AAV expressing shRNA for silencing of Rat Bad.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Bad
Gene Name: BCL2-associated agonist of cell death
Gene ID: 64639
ORF Size: 345 bp
RefSeq#: NM_022698
Gene Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.