rat SAT1 shRNA silencing AAV

Cat. No: shAAV-290039

Availability: 4-5 weeks

Name: AAV-r-SAT1-shRNA

This is an AAV expressing shRNA for silencing of Rat Sat1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Sat1
Gene Name: spermidine/spermine N1-acetyl transferase 1
Gene ID: 302642
Gene Synonyms: Ab2-402; Sat; SSAT
ORF Size: 516 bp
RefSeq#: NM_001007667
Gene Description: Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.