rat IFITM2 shRNA silencing AAV

Cat. No: shAAV-290014

Availability: 4-5 weeks

Name: AAV-r-IFITM2-shRNA

This is an AAV expressing shRNA for silencing of Rat Ifitm2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ifitm2
Gene Name: interferon induced transmembrane protein 2
Gene ID: 114709
Gene Synonyms: Ifitm3l; Ifitml
ORF Size: 435 bp
RefSeq#: NM_030833
Gene Description: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.