mouse SMG7 shRNA silencing AAV

Cat. No: shAAV-281116

Availability: 4-5 weeks

Name: AAV-m-SMG7-shRNA

This is an AAV expressing shRNA for silencing of Mouse Smg7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Smg7
Gene Name: Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
Gene ID: 226517
Gene Synonyms: 9430023P16Rik; mKIAA0250
ORF Size: 3405 bp
RefSeq#: NM_001005507
Gene Description: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
UniGene ID: Mm.270775