mouse CDH1 shRNA silencing AAV

Cat. No: shAAV-280631

Availability: 6-8 weeks

Name: AAV-m-CDH1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cdh1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cdh1
Gene Name: cadherin 1
Gene ID: 12550
Gene Synonyms: AA960649; ARC-1; E-cad; Ecad; L-CAM; Um; UVO
ORF Size: 2655 bp
RefSeq#: NM_009864
Gene Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7|Function: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
UniGene ID: Mm.35605