mouse KLKB1 shRNA silencing AAV

Cat. No: shAAV-280460

Availability: 6-8 weeks

Name: AAV-m-KLKB1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Klkb1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Klkb1
Gene Name: kallikrein B, plasma 1
Gene ID: 16621
Gene Synonyms: APS; Kal-3; Kal3; Klk3; PSA
ORF Size: 1917 bp
RefSeq#: NM_008455
Gene Description: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
UniGene ID: Mm.