mouse UGT1A1 shRNA silencing AAV

Cat. No: shAAV-278232

Availability: 6-8 weeks

Name: AAV-m-UGT1A1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ugt1a1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ugt1a1
Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Gene ID: 394436
Gene Synonyms: Gnt1; UDPGT 1-1; Udpgt-1a; UGT1A01; UgtBr1
ORF Size: 1608 bp
RefSeq#: NM_201645
Gene Description: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.
UniGene ID: Mm.