mouse ARG2 shRNA silencing AAV

Cat. No: shAAV-278070

Availability: 4-5 weeks

Name: AAV-m-ARG2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Arg2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Arg2
Gene Name: arginase type II
Gene ID: 11847
Gene Synonyms: AII; AU022422
ORF Size: 1065 bp
RefSeq#: NM_009705
Gene Description: ARG2 may play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
UniGene ID: Mm.3506