mouse E2F8 shRNA silencing AAV

Cat. No: shAAV-277528

Availability: 4-5 weeks

Name: AAV-m-E2F8-shRNA

This is an AAV expressing shRNA for silencing of Mouse E2f8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: E2f8
Gene Name: E2F transcription factor 8
Gene ID: 108961
Gene Synonyms: 4432406C08Rik; AA410048
ORF Size: 2583 bp
RefSeq#: NM_001013368
Gene Description: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
UniGene ID: Mm.240566