mouse ZFYVE20 shRNA silencing AAV

Cat. No: shAAV-277045

Availability: 4-5 weeks

Name: AAV-m-ZFYVE20-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rbsn.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rbsn
Gene Name: rabenosyn, RAB effector
Gene ID: 78287
Gene Synonyms: 5330426D11Rik; Zfyve20
ORF Size: 2352 bp
RefSeq#: NM_030081
Gene Description: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
UniGene ID: Mm.290734