mouse VDR shRNA silencing AAV

Cat. No: shAAV-275991

Availability: 4-5 weeks

Name: AAV-m-VDR-shRNA

This is an AAV expressing shRNA for silencing of Mouse Vdr.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Vdr
Gene Name: vitamin D receptor
Gene ID: 22337
Gene Synonyms: Nr1i1
ORF Size: 1269 bp
RefSeq#: NM_009504
Gene Description: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
UniGene ID: Mm.245084