mouse DNAJA3 shRNA silencing AAV

Cat. No: shAAV-275968

Availability: 4-5 weeks

Name: AAV-m-DNAJA3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dnaja3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dnaja3
Gene Name: DnaJ heat shock protein family (Hsp40) member A3
Gene ID: 83945
Gene Synonyms: 1200003J13Rik; 1810053A11Rik; C81173; Tid-1; Tid1l
ORF Size: 1362 bp
RefSeq#: NM_023646
Gene Description: Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
UniGene ID: Mm.248337