mouse UNC119 shRNA silencing AAV

Cat. No: shAAV-275629

Availability: 4-5 weeks

Name: AAV-m-UNC119-shRNA

This is an AAV expressing shRNA for silencing of Mouse Unc119.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Unc119
Gene Name: unc-119 lipid binding chaperone
Gene ID: 22248
Gene Synonyms: D11Bhm52; HRG4; MRG4; Rg4; Rtg4; Unc119h
ORF Size: 723 bp
RefSeq#: NM_011676
Gene Description: Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.
UniGene ID: Mm.284811