mouse UBE2M shRNA silencing AAV

Cat. No: shAAV-275487

Availability: 4-5 weeks

Name: AAV-m-UBE2M-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ube2m.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ube2m
Gene Name: ubiquitin-conjugating enzyme E2M
Gene ID: 22192
Gene Synonyms: 2510040H03Rik; Ubc-rs2; UBC12
ORF Size: 309 bp
RefSeq#: NM_145578
Gene Description: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.
UniGene ID: Mm.196580