mouse U2AF1 shRNA silencing AAV

Cat. No: shAAV-275419

Availability: 6-8 weeks

Name: AAV-m-U2AF1-shRNA

This is an AAV expressing shRNA for silencing of Mouse U2af1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: U2af1
Gene Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
Gene ID: 108121
Gene Synonyms: 2010107D16Rik; 35kDa
ORF Size: 720 bp
RefSeq#: NM_024187
Gene Description: Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
UniGene ID: Mm.379289