mouse TXNDC2 shRNA silencing AAV

Cat. No: shAAV-275387

Availability: 6-8 weeks

Name: AAV-m-TXNDC2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Txndc2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Txndc2
Gene Name: thioredoxin domain containing 2 (spermatozoa)
Gene ID: 213272
Gene Synonyms: AU021712; Sptrx-1; Sptrx1; Trx4
ORF Size: 1548 bp
RefSeq#: NM_153519
Gene Description: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
UniGene ID: Mm.255732