mouse TNFSF10 shRNA silencing AAV

Cat. No: shAAV-274720

Availability: 6-8 weeks

Name: AAV-m-TNFSF10-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tnfsf10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tnfsf10
Gene Name: tumor necrosis factor (ligand) superfamily, member 10
Gene ID: 22035
Gene Synonyms: A330042I21Rik; AI448571; APO-2L; Ly81; TL2; Tnlg6a; Trail
ORF Size: 876 bp
RefSeq#: NM_009425
Gene Description: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
UniGene ID: Mm.1062