mouse TINF2 shRNA silencing AAV

Cat. No: shAAV-274238

Availability: 4-5 weeks

Name: AAV-m-TINF2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tinf2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tinf2
Gene Name: Terf1 (TRF1)-interacting nuclear factor 2
Gene ID: 28113
Gene Synonyms: AW552114; D14Wsu146e; Tin2
ORF Size: 1245 bp
RefSeq#: NM_145705
Gene Description: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.
UniGene ID: Mm.29346