mouse TAF1 shRNA silencing AAV

Cat. No: shAAV-273637

Availability: 6-8 weeks

Name: AAV-m-TAF1-shRNA

This is an AAV expressing shRNA for silencing of Mouse TAF1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: TAF1
Gene Name: TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene ID: 270627
Gene Synonyms: 250kDa; AU015687; B430306D02Rik; Ccg-1; Ccg1; KAT4; N-TAF1; Taf2a; TAFII250;
ORF Size: 5706 bp
RefSeq#: NM_001081008
Gene Description: Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.
UniGene ID: Mm.261750