mouse STRA6 shRNA silencing AAV

Cat. No: shAAV-273380

Availability: 6-8 weeks

Name: AAV-m-STRA6-shRNA

This is an AAV expressing shRNA for silencing of Mouse Stra6.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Stra6
Gene Name: stimulated by retinoic acid gene 6
Gene ID: 20897
Gene Synonyms: AI891933
ORF Size: 2013 bp
RefSeq#: NM_009291
Gene Description: STRA6 may act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity).
UniGene ID: Mm.10801