mouse STIM1 shRNA silencing AAV

Cat. No: shAAV-273323

Availability: 4-5 weeks

Name: AAV-m-STIM1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Stim1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Stim1
Gene Name: stromal interaction molecule 1
Gene ID: 20866
Gene Synonyms: SIM
ORF Size: 2058 bp
RefSeq#: NM_009287
Gene Description: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
UniGene ID: Mm.645