mouse STAM2 shRNA silencing AAV

Cat. No: shAAV-273271

Availability: 4-5 weeks

Name: AAV-m-STAM2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Stam2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Stam2
Gene Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Gene ID: 56324
Gene Synonyms: 1200004O12Rik; 5730456G07Rik; BB145015; Hbp
ORF Size: 1572 bp
RefSeq#: NM_019667
Gene Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
UniGene ID: Mm.263639