mouse SPDYA shRNA silencing AAV

Cat. No: shAAV-272973

Availability: 6-8 weeks

Name: AAV-m-SPDYA-shRNA

This is an AAV expressing shRNA for silencing of Mouse Spdya.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Spdya
Gene Name: speedy/RINGO cell cycle regulator family, member A
Gene ID: 70891
Gene Synonyms: 4921517J08Rik; 4930548B21Rik; GS4; MLZ-465; Spdy1
ORF Size: 852 bp
RefSeq#: NM_029254
Gene Description: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2.
UniGene ID: Mm.477599