mouse SPC25 shRNA silencing AAV

Cat. No: shAAV-272967

Availability: 4-5 weeks

Name: AAV-m-SPC25-shRNA

This is an AAV expressing shRNA for silencing of Mouse Spc25.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Spc25
Gene Name: SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Gene ID: 66442
Gene Synonyms: 2600017H08Rik; 2610205L13Rik; Spbc25
ORF Size: 681 bp
RefSeq#: NM_025565
Gene Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
UniGene ID: Mm.272969