mouse SLC24A2 shRNA silencing AAV

Cat. No: shAAV-272177

Availability: 6-8 weeks

Name: AAV-m-SLC24A2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Slc24a2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Slc24a2
Gene Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Gene ID: 76376
Gene Synonyms: 2810021B17Rik; 6330417K15Rik; AI847460; Nckx2
ORF Size: 2136 bp
RefSeq#: NM_172426
Gene Description: Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
UniGene ID: Mm.127296