mouse SIRT3 shRNA silencing AAV

Cat. No: shAAV-272009

Availability: 4-5 weeks

Name: AAV-m-SIRT3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Sirt3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Sirt3
Gene Name: sirtuin 3
Gene ID: 64384
Gene Synonyms: 2310003L23Rik; AI848213; Sir2l3
ORF Size: 774 bp
RefSeq#: NM_022433
Gene Description: NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
UniGene ID: Mm.244216