mouse SIRT2 shRNA silencing AAV

Cat. No: shAAV-272008

Availability: 6-8 weeks

Name: AAV-m-SIRT2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Sirt2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Sirt2
Gene Name: sirtuin 2
Gene ID: 64383
Gene Synonyms: 5730427M03Rik; Sir2l; SIR2L2
ORF Size: 1170 bp
RefSeq#: NM_022432
Gene Description: NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.
UniGene ID: Mm.272443