mouse SH3PXD2B shRNA silencing AAV

Cat. No: shAAV-271918

Availability: 4-5 weeks

Name: AAV-m-SH3PXD2B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Sh3pxd2b.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Sh3pxd2b
Gene Name: SH3 and PX domains 2B
Gene ID: 268396
Gene Synonyms: fad49; G431001E03Rik; TSK4
ORF Size: 2727 bp
RefSeq#: NM_177364
Gene Description: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).
UniGene ID: Mm.227616