mouse SF3B2 shRNA silencing AAV

Cat. No: shAAV-271782

Availability: 4-5 weeks

Name: AAV-m-SF3B2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Sf3b2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Sf3b2
Gene Name: splicing factor 3b, subunit 2
Gene ID: 319322
Gene Synonyms: 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; SAP145; SF3b1; SF3b145; SF3b150
ORF Size: 2637 bp
RefSeq#: NM_030109
Gene Description: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
UniGene ID: Mm.471551