mouse RTCD1 shRNA silencing AAV

Cat. No: shAAV-271203

Availability: 4-5 weeks

Name: AAV-m-RTCD1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rtca.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rtca
Gene Name: RNA 3'-terminal phosphate cyclase
Gene ID: 66368
Gene Synonyms: 2310009A18Rik; AI450277; RPC; Rtcd1
ORF Size: 1101 bp
RefSeq#: NM_025517
Gene Description: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
UniGene ID: Mm.251228