mouse RSAD2 shRNA silencing AAV

Cat. No: shAAV-271168

Availability: 4-5 weeks

Name: AAV-m-RSAD2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rsad2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rsad2
Gene Name: radical S-adenosyl methionine domain containing 2
Gene ID: 58185
Gene Synonyms: 2510004L01Rik; cig5; Vig1
ORF Size: 1089 bp
RefSeq#: NM_021384
Gene Description: Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
UniGene ID: Mm.24045