mouse RP2H shRNA silencing AAV

Cat. No: shAAV-270817

Availability: 4-5 weeks

Name: AAV-m-RP2H-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rp2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rp2
Gene Name: retinitis pigmentosa 2 homolog
Gene ID: 19889
Gene Synonyms: AI662636; Rp2h
ORF Size: 1044 bp
RefSeq#: NM_133669
Gene Description: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
UniGene ID: Mm.288141