mouse RCC1 shRNA silencing AAV

Cat. No: shAAV-270315

Availability: 4-5 weeks

Name: AAV-m-RCC1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rcc1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rcc1
Gene Name: regulator of chromosome condensation 1
Gene ID: 100088
Gene Synonyms: 4931417M11Rik; AI326872; Chc1
ORF Size: 1305 bp
RefSeq#: NM_133878
Gene Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
UniGene ID: Mm.255045