mouse RAD51L1 shRNA silencing AAV

Cat. No: shAAV-270066

Availability: 6-8 weeks

Name: AAV-m-RAD51L1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rad51b.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rad51b
Gene Name: RAD51 paralog B
Gene ID: 19363
Gene Synonyms: AI553500; mREC2; R51H2; Rad51l1
ORF Size: 747 bp
RefSeq#: NM_009014
Gene Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
UniGene ID: Mm.341756