mouse PTN shRNA silencing AAV

Cat. No: shAAV-269773

Availability: 4-5 weeks

Name: AAV-m-PTN-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ptn.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ptn
Gene Name: pleiotrophin
Gene ID: 19242
Gene Synonyms: HARP; HB-GAM; HBBN; HBGF-8; HBNF; OSF; Osf-1; Osf1
ORF Size: 507 bp
RefSeq#: NM_008973
Gene Description: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
UniGene ID: Mm.279690