mouse PTBP2 shRNA silencing AAV

Cat. No: shAAV-269713

Availability: 4-5 weeks

Name: AAV-m-PTBP2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ptbp2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ptbp2
Gene Name: polypyrimidine tract binding protein 2
Gene ID: 56195
Gene Synonyms: brPTB; nPTB; Ptb2
ORF Size: 1596 bp
RefSeq#: NM_019550
Gene Description: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
UniGene ID: Mm.29966