mouse PQBP1 shRNA silencing AAV

Cat. No: shAAV-269280

Availability: 4-5 weeks

Name: AAV-m-PQBP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pqbp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pqbp1
Gene Name: polyglutamine binding protein 1
Gene ID: 54633
Gene Synonyms: npw38; PQBP-1; Sfc2
ORF Size: 792 bp
RefSeq#: NM_019478
Gene Description: PQBP1 may suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
UniGene ID: Mm.14616