mouse PPP1R1A shRNA silencing AAV

Cat. No: shAAV-269206

Availability: 6-8 weeks

Name: AAV-m-PPP1R1A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ppp1r1a.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ppp1r1a
Gene Name: protein phosphatase 1, regulatory (inhibitor) subunit 1A
Gene ID: 58200
Gene Synonyms: 0610038N18Rik; I-1
ORF Size: 516 bp
RefSeq#: NM_021391
Gene Description: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
UniGene ID: Mm.143788