mouse PINK1 shRNA silencing AAV

Cat. No: shAAV-268677

Availability: Immediate

Name: AAV-m-PINK1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pink1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pink1
Gene Name: PTEN induced putative kinase 1
Gene ID: 68943
Gene Synonyms: 1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387
ORF Size: 1743 bp
RefSeq#: NM_026880
Gene Description: Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation.
UniGene ID: Mm.18539